4.4 Article

Inhibitory Activity against Urease of Quercetin Glycosides Isolated from Allium cepa and Psidium guajava

Journal

BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY
Volume 74, Issue 4, Pages 878-880

Publisher

TAYLOR & FRANCIS LTD
DOI: 10.1271/bbb.90895

Keywords

urease inhibitor; quercetin; flavonoid; quercetin glycoside; edible plant

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Methanolic extracts of edible plants and seaweeds were tested for their inhibitory activity against Jack bean urease. Quercetin-4'-O-beta-D-glucopyranoside was isolated from Allium cepa as a urease inhibitor with an IC50 value of 190 mu M. Quercetin and two quercetin glycosides, avicularin and guaijaverin, were isolated from Psidium guajava as urease inhibitors with respective IC50 values of 80 mu M, 140 mu M, and 120 mu M.

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