Journal
BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY
Volume 73, Issue 8, Pages 1866-1868Publisher
TAYLOR & FRANCIS LTD
DOI: 10.1271/bbb.90095
Keywords
Psilocybe argentipes; hallucinogenic mushrooms; psilocybin; marble-burying behavior; obsessive-compulsive disorder
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Funding
- Kakenhi Research [20580180]
- Asao Health Promotion Foundation
- Grants-in-Aid for Scientific Research [20580180] Funding Source: KAKEN
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Psilocybe argentipes is a hallucinogenic mushroom. The present study examined the effects of P. argentipes on marble-burying behavior, which is considered an animal model of obsessive-compulsive disorder. P. argentipes significantly inhibited marble-burying behavior without affecting locomotor activity as compared with the same dose of authentic psilocybin. These findings suggest that P. argentipes would be efficient in clinical obsessive-compulsive disorder therapy.
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