Journal
BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY
Volume 73, Issue 8, Pages 1898-1900Publisher
TAYLOR & FRANCIS LTD
DOI: 10.1271/bbb.90228
Keywords
aspochracin; sponge; Demospongiae; Aspergillus sclerotiorum
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Funding
- New Energy and Industrial Technology Department Organization (NEDO) of Japan
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In the course of our chemical screening program for novel metabolites by LC-MS monitoring, we isolated a new aspochracin derivative, JBIR-15 (1), together with aspochracin, from the culture broth of a sponge-derived fungus, Aspergillus sclerotiorum Huber Sp080903f04. The structure of 1 was determined to be N-demethyl aspochracin at the alanyl residue on the basis of extensive NMR and MS analyses.
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