Journal
BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY
Volume 73, Issue 1, Pages 230-232Publisher
TAYLOR & FRANCIS LTD
DOI: 10.1271/bbb.80617
Keywords
DPPH radical-scavenger; Streptomyces sp USF-6280; surugapyrrole A; surugapyrrole B; N-hydroxypyrrole
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Two new N-hydroxypyrroles, surugapyrroles A and B, were isolated as DPPH radical-scavengers from a culture broth of Streptomyces sp. USF-6280 strain. The structures of the two compounds were elucidated by spectroscopic evidences and derivatization. Their DPPH (2,2-diphenyl-1-picrylhydrazyl) radical-scavenging activity was as high as that of butylhydroxytoluene (BHT): surugapyrrole A, ED50 50.3 mu M; surugapyrrole B, ED50 75.8 mu M.
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