Journal
BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY
Volume 73, Issue 10, Pages 2335-2337Publisher
TAYLOR & FRANCIS LTD
DOI: 10.1271/bbb.90365
Keywords
alkyl gallates; hyaluronidase inhibitory activity; collagenase inhibitory activity; antioxidant activity
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A series of the gallate esters of n-alkanols (C-1-C-12) was examined to determine their inhibitory activities against hyaluronidase and collagenase. Hexyl, heptyl, octyl, nonyl, and decyl gallates inhibited both hyaluronidase and collagenase, and the most potent inhibitor was octyl gallate against both enzymes. Octyl 3,5-dihydroxybenzoate showed inhibitory effects on hyaluronidase, whereas collagenase was inhibited by octyl 3,4-dihydroxybenzoate.
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