Journal
BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY
Volume 73, Issue 2, Pages 431-433Publisher
TAYLOR & FRANCIS LTD
DOI: 10.1271/bbb.80556
Keywords
royal jelly; pituitary; prolactin; aging; thyroid-stimulating hormone beta
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To determine the effects of ingested royal Jelly (RJ) on the pituitary in middle-aged female rats, we performed a long-term RJ administration test. Several animals showed age-related increases in pituitary weight, and RJ administration compensated for the increase. RJ tended to down-regulate prolactin mRNA and up-regulated thyroid-stimulating hormone beta mRNA in the pituitary. This suggests that RJ compensates for age-associated decline in pituitary functions.
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