Journal
BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY
Volume 72, Issue 11, Pages 3011-3014Publisher
TAYLOR & FRANCIS LTD
DOI: 10.1271/bbb.80301
Keywords
citrate fermentation; anaerobic regulation; two-component signal transduction; CitA/CitB; Escherichia coli
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Funding
- Ministry of Education, Culture, Sports, Science, and Technology of Japan [18770157]
- Grants-in-Aid for Scientific Research [18770157] Funding Source: KAKEN
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In Escherichia coli, CitB, a cognate response regulator of CitA, specifically bound to the promoter regions for mdh, citA, citC, and exuT. Transcription of these genes was induced by citrate under anaerobic conditions in a CitAB-dependent manner. Taking this together, we conclude that CitAB is the master regulatory system that activates the set of genes involved in citrate fermentation in E. coli.
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