Journal
BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY
Volume 72, Issue 11, Pages 2998-3001Publisher
TAYLOR & FRANCIS LTD
DOI: 10.1271/bbb.80146
Keywords
Aspergillus oryzae; solid-state culture; submerged culture; unfolded protein response; quantitative real-time PCR
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Funding
- National Natural Science Foundation of China [30770057]
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The unfolded protein response (UPR) is a regulatory system to maintain the homeostasis of ER functions. Here we report a comparison of express levels of UPR relevant genes in Aspergillus oryzae between solid-state and submerged cultivation. The results were that up-regulation of the UPR mechanism in solid-state culture was higher than in submerged culture (heat-shock or non-stress conditions). This might have been a result of changing culture conditions.
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