Journal
BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY
Volume 72, Issue 11, Pages 2981-2986Publisher
TAYLOR & FRANCIS LTD
DOI: 10.1271/bbb.80461
Keywords
lignan; antioxidant activity; dihydroguaiaretic acid
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Funding
- Consortium R&D Project for Regional Revitalization
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The antioxidant activity of butane-type lignans was evaluated. Secoisolariciresinol (SECO) and dihydroguaiaretic acid (DGA) showed higher radical scavenging activity than that of 7,7'-dioxodihydroguaiaretic acid (ODGA). SECO and DGA inhibited the oxidation of unsaturated fatty acid. Both enantiomers of DGA were also lipoxygenase inhibitors, but neither enantiomer of SECO inhibited the lipoxygenase activity.
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