Journal
CHEMICAL RECORD
Volume 18, Issue 5, Pages 543-554Publisher
WILEY-V C H VERLAG GMBH
DOI: 10.1002/tcr.201700047
Keywords
Alkaloids; lycopodium; fawcettimine; natural product; total synthesis
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Funding
- National Key Research and Development Program of China [2017YFA0505200]
- National High Technology Project 973 [2015CB856200]
- NNSFC [21472010, 21521003, 21561142002, 21625201]
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Ever since the pioneering synthetic work reported by both Inubushi and Heathcock back in 1980s, the fawcettimine-type Lycopodium alkaloids have continuously served as a driving force for discoveries in organic synthesis. In this personal account, we summarized our recent synthetic efforts towards the total synthesis of fawcettimine-type Lycopodium alkaloids, along with a brief summary of relevant syntheses reported by others. Our discussions focus mainly on the key reactions applied during the synthesis of fawcettimine-type Lycopodium alkaloids.
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