Journal
ACS APPLIED MATERIALS & INTERFACES
Volume 7, Issue 22, Pages 12176-12183Publisher
AMER CHEMICAL SOC
DOI: 10.1021/acsami.5b02542
Keywords
mussel-inspired; dopamine; electrospinning nanofiber; wound healing; silver nanoparticles
Funding
- Basic Science Research Program through the National Research Foundation of Korea (NRF) - Ministry of Education, Science, and Technology [2013-012911, 2013R1A2A2A04015484]
- National Research Foundation of Korea [22A20130012537, 2013R1A1A2012911, 2013R1A2A2A04015484] Funding Source: Korea Institute of Science & Technology Information (KISTI), National Science & Technology Information Service (NTIS)
Ask authors/readers for more resources
Electrospun nanofibers that contain silver nanoparticles (AgNPs) have a strong antibacterial activity that is beneficial to wound healing. However, most of the literature available on the bactericidal effects of this material is based on the use of AgNPs with uncontrolled Size, shape, surface properties, and degree of aggregation. In this study, we report the first versatile synthesis of novel catechol moieties presenting electrospun nanofibers functionalized with AgNPs through catechol redox chemistry. The synthetic strategy allows control of the size and amount of AgNPs on the surface of nanofibers with the minimum degree of aggregation. We also evaluated the rate of release of the AgNPs, the biocompatibility of the nanofibers, the antibacterial activity in vitro, and the wound healing capacity in vivo. Our results suggest that these, silver-releasing nanofibers have,great potential for use in wound healing applications.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available