Journal
BRIEFINGS IN FUNCTIONAL GENOMICS
Volume 17, Issue 1, Pages 64-76Publisher
OXFORD UNIV PRESS
DOI: 10.1093/bfgp/elx019
Keywords
single-cell technologies; genomics; RNA sequencing
Funding
- Israel Science Foundation [1902/12, 1634/13, 2017/13]
- Israel Cancer Association [20150911]
- Israel Ministry of Health [3-10146]
- EU-FP7 (Marie Curie International Reintegration Grant) [618592]
- Department of Biotechnology, India
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In recent years, there has been an effort to develop new technologies for measuring gene expression and sequence information from thousands of individual cells. Large data sets that were obtained using these 'single cell' technologies have allowed scientists to address fundamental questions in biomedicine ranging from stems cells and development to cancer and immunology. Here, we provide a brief review of recent developments in single-cell technology. Our intention is to provide a quick background for newcomers to the field as well as a deeper description of some of the leading technologies to date.
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