4.8 Article

Incorporating catechol into electroactive polypyrrole nanowires on titanium to promote hydroxyapatite formation

Journal

BIOACTIVE MATERIALS
Volume 3, Issue 1, Pages 74-79

Publisher

KEAI PUBLISHING LTD
DOI: 10.1016/j.bioactmat.2017.05.006

Keywords

Titanium; Hydroxyapatite; Nanowires; Catechol; Polypyrrole

Funding

  1. National Natural Science Foundation of China [51372087, 51541201]
  2. National High Technology Research and Development Program of China (863 Program) [2015AA033502]
  3. Science and technology program of Guangzhou [201707010200]
  4. Natural Science Foundation of Guangdong Province [2016A030308014]

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To improve the osteointegration property of biomedical titanium, nano-architectured electroactive coating was synthesized through the electrochemical polymerization of dopamine and pyrrole. The highly binding affinity of Ca2+ to the catechol moiety of doped dopamine enabled efficient interaction between polypyrrole/polydopamine nanowires and mineral ions. The results indicate that the PPy/PDA nanowires preserved its efficient electro-activity and accelerated the hydroxyapatite deposition in a simulated body fluid. The PPy/PDA nanowires coating could be applied to promote the osteointegration of titanium implant. (c) 2018 The Authors. Production and hosting by Elsevier B.V. on behalf of KeAi Communications Co., Ltd.

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