Journal
BIORESOURCE TECHNOLOGY
Volume 100, Issue 4, Pages 1687-1690Publisher
ELSEVIER SCI LTD
DOI: 10.1016/j.biortech.2008.09.002
Keywords
Sugarcane bagasse; Bagasse cellulose sulfates; Anticoagulation; Ionic liquid; Degree of substitution
Funding
- The 11th Five-Year Plan National Science and Technology [2006BAD05A02]
- Guangdong Provincial Natural Science Fund [05300177]
- Hong Kong Polytechnic University Niche Area Projects [1-BB80]
Ask authors/readers for more resources
Homogeneous sulfation of bagasse cellulose (BC) with chlorosulfonic acid-dimethylformamide was accomplished in an ionic liquid 1-butyl-3-methylimidazolium chloride ([C(4)mim]Cl). The BCS products from the sulfation had degrees of substitution (DS) in the range of 0.52-2.95 and a simultaneous substitution pattern at C-6, C-2 and C-3 positions. The sulfated BCS attained significant anticoagulation activity, Causing a dose-dependent prolongation of coagulation time and inhibition of FIIa and FXa activities in human plasma. The anticoagulation activity of BCS showed a positive correlation with DS, and some of the activity indexes exceeded those of heparin. (C) 2008 Elsevier Ltd. All rights reserved.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available
Share Paper
