Related references
Note: Only part of the references are listed.Synthesis and Screening of a Haloacetamidine Containing Library To Identify PAD4 Selective Inhibitors
Justin E. Jones et al.
ACS CHEMICAL BIOLOGY (2012)
Peptidylarginine deiminase 2, 3 and 4 have distinct specificities against cellular substrates: novel insights into autoantigen selection in rheumatoid arthritis
Erika Darrah et al.
ANNALS OF THE RHEUMATIC DISEASES (2012)
Neutrophil Extracellular Traps That Are Not Degraded in Systemic Lupus Erythematosus Activate Complement Exacerbating the Disease
Jonatan Leffler et al.
JOURNAL OF IMMUNOLOGY (2012)
Regulation of histone modification and chromatin structure by the p53-PADI4 pathway
Chizu Tanikawa et al.
NATURE COMMUNICATIONS (2012)
Kinase Consensus Sequences: A Breeding Ground for Crosstalk
Heather L. Rust et al.
ACS CHEMICAL BIOLOGY (2011)
Suppression of colitis in mice by Cl-amidine: a novel peptidylarginine deiminase inhibitor
Alexander A. Chumanevich et al.
AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY (2011)
Autodeimination of Protein Arginine Deiminase 4 Alters Protein-Protein Interactions but Not Activity
Jessica L. Slack et al.
BIOCHEMISTRY (2011)
Protein arginine deiminase 4: a target for an epigenetic cancer therapy
Jessica L. Slack et al.
CELLULAR AND MOLECULAR LIFE SCIENCES (2011)
Protein deiminases: New players in the developmentally regulated loss of neural regenerative ability
Sigrun Lange et al.
DEVELOPMENTAL BIOLOGY (2011)
Citrullination of Inhibitor of Growth 4 (ING4) by Peptidylarginine Deminase 4 (PAD4) Disrupts the Interaction between ING4 and p53
Qin Guo et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2011)
N-α-Benzoyl-N5-(2-Chloro-1-Iminoethyl)-L-Ornithine Amide, a Protein Arginine Deiminase Inhibitor, Reduces the Severity of Murine Collagen-Induced Arthritis
Van C. Willis et al.
JOURNAL OF IMMUNOLOGY (2011)
The Development of N-α-(2-Carboxyl)benzoyl-N5-(2-fluoro-1-iminoethyl)-L-ornithine Amide (o-F-amidine) and N-α-(2-Carboxyl)benzoyl-N5-(2-chloro-1-iminoethyl)-L-ornithine Amide (o-Cl-amidine) As Second Generation Protein Arginine Deiminase (PAD) Inhibitors
Corey P. Causey et al.
JOURNAL OF MEDICINAL CHEMISTRY (2011)
Subcellular Localization of Peptidylarginine Deiminase 2 and Citrullinated Proteins in Brains of Scrapie-Infected Mice: Nuclear Localization of PAD2 and Membrane Fraction-Enriched Citrullinated Proteins
Byungki Jang et al.
JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY (2011)
On the Mechanism of Dimethylarginine Dimethylaminohydrolase Inactivation by 4-Halopyridines
Corey M. Johnson et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2011)
Discovery of peptidylarginine deiminase-4 substrates by protein array: antagonistic citrullination and methylation of human ribosomal protein S2
Qin Guo et al.
MOLECULAR BIOSYSTEMS (2011)
Neutrophils in the pathogenesis and manifestations of SLE
Mariana J. Kaplan
NATURE REVIEWS RHEUMATOLOGY (2011)
PAD4-Mediated Neutrophil Extracellular Trap Formation Is Not Required for Immunity against Influenza Infection
Saskia Hemmers et al.
PLOS ONE (2011)
Long pentraxin 3 (PTX3) expression and release by neutrophils in vitro and in ulcerative colitis
Alexander S. Savchenko et al.
PATHOLOGY INTERNATIONAL (2011)
Autocitrullination of Human Peptidyl Arginine Deiminase Type 4 Regulates Protein Citrullination During Cell Activation
Felipe Andrade et al.
ARTHRITIS AND RHEUMATISM (2010)
Substrate Specificity and Kinetic Studies of PADs 1, 3, and 4 Identify Potent and Selective Inhibitors of Protein Arginine Deiminase 3
Bryan Knuckley et al.
BIOCHEMISTRY (2010)
Haloacetamidine-Based Inactivators of Protein Arginine Deiminase 4 (PAD4): Evidence that General Acid Catalysis Promotes Efficient Inactivation
Bryan Knuckley et al.
CHEMBIOCHEM (2010)
PAD4 is essential for antibacterial innate immunity mediated by neutrophil extracellular traps
Pingxin Li et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2010)
Arginine Metabolising Enzymes as Therapeutic Tools for Alzheimer's Disease: Peptidyl Arginine Deiminase Catalyses Fibrillogenesis of β-amyloid Peptides
Peter Mohlake et al.
MOLECULAR NEUROBIOLOGY (2010)
Potential Role for Peptidylarginine Deiminase 2 (PAD2) in Citrullination of Canine Mammary Epithelial Cell Histones
Brian D. Cherrington et al.
PLoS One (2010)
Global turnover of histone post-translational modifications and variants in human cells
Barry M. Zee et al.
EPIGENETICS & CHROMATIN (2010)
Increased PADI4 expression in blood and tissues of patients with malignant tumors
Xiaotian Chang et al.
BMC CANCER (2009)
Histone hypercitrullination mediates chromatin decondensation and neutrophil extracellular trap formation
Yanming Wang et al.
JOURNAL OF CELL BIOLOGY (2009)
Born-Oppenheimer ab Initio QM/MM Molecular Dynamics Simulations of the Hydrolysis Reaction Catalyzed by Protein Arginine Deiminase 4
Zhihong Ke et al.
JOURNAL OF PHYSICAL CHEMISTRY B (2009)
Active Site Cysteine Is Protonated in the PAD4 Michaelis Complex: Evidence from Born-Oppenheimer Ab Initio QM/MM Molecular Dynamics Simulations
Zhihong Ke et al.
JOURNAL OF PHYSICAL CHEMISTRY B (2009)
Synovial fluid is a site of citrullination of autoantigens in inflammatory arthritis
Andrew Kinloch et al.
ARTHRITIS AND RHEUMATISM (2008)
Profiling Protein Arginine Deiminase 4 (PAD4): A novel screen to identify PAD4 inhibitors
Bryan Knuckley et al.
BIOORGANIC & MEDICINAL CHEMISTRY (2008)
Haplotypes of PADI4 susceptible to rheumatoid arthritis are also associated with ulcerative colitis in the Japanese population
Chun Chuan Chen et al.
CLINICAL IMMUNOLOGY (2008)
Histone Arg modifications and p53 regulate the expression of OKL38, a mediator of apoptosis
Hongjie Yao et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2008)
Histone deimination as a response to inflammatory stimuli in neutrophils
Indira Neeli et al.
JOURNAL OF IMMUNOLOGY (2008)
Regulation of p53 target gene expression by peptidylarginine deiminase 4
Pingxin Li et al.
MOLECULAR AND CELLULAR BIOLOGY (2008)
Protein arginine deiminase 4: Evidence for a reverse protonation mechanism
Bryan Knuckley et al.
BIOCHEMISTRY (2007)
The role of citrullinated proteins suggests a novel mechanism in the pathogenesis of multiple sclerosis
Mario A. Moscarello et al.
NEUROCHEMICAL RESEARCH (2007)
Activity-based protein profiling reagents for protein arginine deiminase 4 (PAD4): Synthesis and in vitro evaluation of a fluorescently labeled probe
Yuan Luo et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2006)
Inhibitors and inactivators of protein arginine deiminase 4: Functional and structural characterization
Yuan Luo et al.
BIOCHEMISTRY (2006)
Structural basis for histone N-terminal recognition by human peptidylarginine deiminase 4
K Arita et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)
Histone citrullination by protein arginine deiminase: Is arginine methylation a green light or a roadblock?
Paul R. Thompson et al.
ACS CHEMICAL BIOLOGY (2006)
Inactivation of two diverse enzymes in the amidinotransferase superfamily by 2-chloroacetamidine: Dimethylargininase and peptidylarginine deiminase
EM Stone et al.
BIOCHEMISTRY (2005)
Kinetic characterization of protein arginine deiminase 4: A transcriptional corepressor implicated in the onset and progression of rheumatoid arthritis
PL Kearney et al.
BIOCHEMISTRY (2005)
Abnormal accumulation of citrullinated proteins catalyzed by peptidylarginine deiminase in hippocampal extracts from patients with Alzheimer's disease
A Ishigami et al.
JOURNAL OF NEUROSCIENCE RESEARCH (2005)
Regulation of coactivator complex assembly and function by protein arginine methylation and demethylimination
YH Lee et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)
Citrullinated proteins have increased immunogenicity and arthritogenicity and their presence in arthritic joints correlates with disease severity
K Lundberg et al.
ARTHRITIS RESEARCH & THERAPY (2005)
Neutrophil extracellular traps kill bacteria
V Brinkmann et al.
SCIENCE (2004)
Structural basis for Ca2+-induced activation of human PAD4
K Arita et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2004)
Citrullinated proteins: sparks that may ignite the fire in rheumatoid arthritis
ER Vossenaar et al.
ARTHRITIS RESEARCH & THERAPY (2004)
Functional haplotypes of PADI4, encoding citrullinating enzyme peptidylarginine deiminase 4, are associated with rheumatoid arthritis
A Suzuki et al.
NATURE GENETICS (2003)
PAD, a growing family of citrullinating enzymes: genes, features and involvement in disease
ER Vossenaar et al.
BIOESSAYS (2003)
Deimination of arginine residues in nucleophosmin/B23 and histones in HL-60 granulocytes
T Hagiwara et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2002)
The major synovial targets of the rheumatoid arthritis-specific antifilaggrin autoantibodies are deiminated forms of the α- and β-chains of fibrin
C Masson-Bessière et al.
JOURNAL OF IMMUNOLOGY (2001)
Genotoxicity of streptonigrin:: a review
AD Bolzán et al.
MUTATION RESEARCH-REVIEWS IN MUTATION RESEARCH (2001)
A colorimetric 96-well microtiter plate assay for the determination of enzymatically formed citrulline
M Knipp et al.
ANALYTICAL BIOCHEMISTRY (2000)
The language of covalent histone modifications
BD Strahl et al.
NATURE (2000)
Share Paper
