Journal
BIOPOLYMERS
Volume 94, Issue 4, Pages 441-447Publisher
WILEY
DOI: 10.1002/bip.21379
Keywords
native chemical ligation; chemical protein synthesis; convergent; protein synthesis
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Funding
- Korean Government [2009-0072688]
- Ministry of Education, Science and Technology
- Posco TJ Park Foundation
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This review examines the challenges in the chemical synthesis of average sized proteins. Recent progress on sequential and convergent ligation methods, two approaches to the synthesis of proteins, is outlined. An examination of these challenges could aid in the process of finding new methodologies for the efficient chemical synthesis of average sized protein molecules.(1-3) (C) 2010 Wiley Periodicals, Inc. Biopolymers (Pept Sci) 94: 441-447, 2010.
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