Journal
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
Volume 57, Issue 1, Pages 203-207Publisher
WILEY-V C H VERLAG GMBH
DOI: 10.1002/anie.201710136
Keywords
amino acids; arylation; palladium; peptides; triazoles
Categories
Funding
- DFG
- CSC
- Alexander von Humboldt foundation
Ask authors/readers for more resources
Secondary C(sp(3))-H arylations were accomplished by palladium catalysis with triazoles as peptide bond isosteres. The unique power of this approach is highlighted by the possibility of achieving secondary C(sp(3))-H functionalizations on terminal peptides as well as the unprecedented positional-selective C(sp(3))-H functionalization of internal peptide positions, setting the stage for modular peptide late-stage diversification.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available