Journal
NEW JOURNAL OF CHEMISTRY
Volume 42, Issue 23, Pages 18889-18893Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/c8nj03822h
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Funding
- CSIR-Senior Research Associateship, New Delhi
- Inspire Junior Research Fellowship, Govt. of India
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This paper describes a mild phenyliodine diacetate mediated method for selective chlorination, bromination, and iodination of indole C-H bonds using sodium halide as a source for analogous halogenations. The combination of NaX and phenyliodine diacetate provides an invincible system for halogenation of indoles. This protocol was compatible with a wide array of indole substrates and provides straight forward access to potential halogenated arenes.
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