4.6 Article

Investigating the breakdown of the nerve agent simulant methyl paraoxon and chemical warfare agents GB and VX using nitrogen containing bases

Journal

ORGANIC & BIOMOLECULAR CHEMISTRY
Volume 16, Issue 47, Pages 9285-9291

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/c8ob02475h

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Funding

  1. Defence Science and Technology Laboratory (Dstl)
  2. EPSRC [EP/L021978/1]
  3. EPSRC [EP/L021978/2] Funding Source: UKRI

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A range of nitrogen containing bases was tested for the hydrolysis of a nerve agent simulant, methyl paraoxon (MP), and the chemical warfare agents, GB and VX. The product distribution was found to be highly dependant on the basicity of the base and the quantity of water used for the hydrolysis. This study is important in the design of decontamination technology, which often involve mimics of CWAs.

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