4.6 Article

Manganese catalyzed N-alkylation of anilines with alcohols: ligand enabled selectivity

Journal

ORGANIC & BIOMOLECULAR CHEMISTRY
Volume 16, Issue 43, Pages 8175-8180

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/c8ob01886c

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Funding

  1. SERB [EMR/2015/000030]
  2. CSIR
  3. UGC
  4. CSIR-INPROTICS PA [HCP0011-A]

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Ligand enabled Earth-abundant manganese catalyzed N-alkylation of amines with alcohols via a hydrogen auto-transfer strategy is reported. The choice of the ligand plays a significant role in the alcohol reactivity (aliphatic or aromatic) toward N-alkylation reactions.

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