4.0 Review

PROOXIDANT ACTIVITIES OF ANTIOXIDANTS AND THEIR IMPACT ON HEALTH

Journal

ACTA CLINICA CROATICA
Volume 58, Issue 4, Pages 726-736

Publisher

SESTRE MILOSRDNICE UNIV HOSPITAL
DOI: 10.20471/acc.2019.58.04.20

Keywords

Oxidative stress; Antioxidants; Diet; Chronic disease; Dietary supplements; Free radicals

Funding

  1. Slovenian Research Agency [P3-0388]

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This review article is focused on the impact of antioxidants and prooxidants on health with emphasis on the type of antioxidants that should be taken. Medical researchers suggest that diet may be the solution for the control of chronic diseases such as cardiovascular complications, hypertension, diabetes mellitus, and different cancers. In this survey, we found scientific evidence that the use of antioxidants should be limited only to the cases where oxidative stress has been identified. This is often the case of specific population groups such as postmenopausal women, the elderly, infants, workers exposed to environmental pollutants, and the obese. Before starting any supplementation, it is necessary to measure oxidative stress and to identify and eliminate the possible sources of free radicals and thus increased oxidative stress.

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