Related references
Note: Only part of the references are listed.Utility of a physiologically-based pharmacokinetic (PBPK) modeling approach to quantitatively predict a complex drug-drug-disease interaction scenario for rivaroxaban during the drug review process: implications for clinical practice
Joseph A. Grillo et al.
BIOPHARMACEUTICS & DRUG DISPOSITION (2012)
Role of Modelling and Simulation
Siv Jönsson et al.
CLINICAL PHARMACOKINETICS (2012)
Evaluation of Exposure Change of Nonrenally Eliminated Drugs in Patients With Chronic Kidney Disease Using Physiologically Based Pharmacokinetic Modeling and Simulation
Ping Zhao et al.
JOURNAL OF CLINICAL PHARMACOLOGY (2012)
Interplay of Metabolism and Transport in Determining Oral Drug Absorption and Gut Wall Metabolism: A Simulation Assessment Using the “Advanced Dissolution, Absorption, Metabolism (ADAM)” Model
A. S. Darwich et al.
CURRENT DRUG METABOLISM (2011)
Population-Based Mechanistic Prediction of Oral Drug Absorption
Masoud Jamei et al.
AAPS JOURNAL (2009)
The Simcyp® Population-based ADME Simulator
Masoud Jamei et al.
EXPERT OPINION ON DRUG METABOLISM & TOXICOLOGY (2009)
Estimation of effective intestinal membrane permeability considering bile micelle solubilisation
Kiyohiko Sugano
INTERNATIONAL JOURNAL OF PHARMACEUTICS (2009)
Cytochrome P450 turnover: Regulation of synthesis and degradation, methods for determining rates, and implications for the prediction of drug interactions
Jiansong Yang et al.
CURRENT DRUG METABOLISM (2008)
Prediction of intestinal first-pass drug metabolism
Jiansong Yang et al.
CURRENT DRUG METABOLISM (2007)
Implications of mechanism-based inhibition of CYP2D6 for the pharmacokinetics and toxicity of MDMA
Jiansong Yang et al.
JOURNAL OF PSYCHOPHARMACOLOGY (2006)
Physiologically based pharmacokinetic modelling 2: Predicting the tissue distribution of acids, very weak bases, neutrals and zwitterions
Trudy Rodgers et al.
JOURNAL OF PHARMACEUTICAL SCIENCES (2006)
The utility of in vitro cytochrome P450 inhibition data in the prediction of drug-drug interactions
RS Obach et al.
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2006)
Physiologically based pharmacokinetic modeling 1: Predicting the tissue distribution of moderate-to-strong bases
T Rodgers et al.
JOURNAL OF PHARMACEUTICAL SCIENCES (2005)
Cytochrome P450 3A expression and activity in the human small intestine
JS Yang et al.
CLINICAL PHARMACOLOGY & THERAPEUTICS (2004)
Predicting the impact of physiological and biochemical processes on oral drug bioavailability
B Agoram et al.
ADVANCED DRUG DELIVERY REVIEWS (2001)
Share Paper
