Aggressive osteolytic lesion of mandible - A case report

Odontogenic tumors are rare entities, often derived from epithelial remnants in the gnathic bones following odontogenesis. Ameloblastoma is benign locally invasive accounting for 1% of tumors of jaws. Among the various ameloblastoma, solid multicystic ameloblastoma is believed to be locally aggressive lesion that has the tendency for recurrence. In this report, we present a large aggressive solid multicystic ameloblastoma in a 33-year-old male patient diagnosed by computed tomography and successfully managed by hemimandibulectomy with simultaneous reconstruction using fibula. We have also briefly discussed the molecular pathogenesis and new treatment aspects of ameloblastoma.