Journal
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
Volume 24, Issue 17, Pages 4298-4303Publisher
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.bmcl.2014.07.023
Keywords
Green synthesis; Coptidis Rhizome; Antibacterial; Antioxidant; Cytotoxic activity
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Funding
- Dongguk University
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Here, we report a simple, eco-friendly and inexpensive approach for the synthesis of zinc oxide nanopartides (ZnO NPs) using Coptidis Rhizome. The ZnO NPs were characterized by UV-visible absorption spectroscopy, FTIR, SEM-EDX, TGA, TEM, SAED and XRD. TEM images confirmed the presence of spherical and rod shaped ZnO NPs in the range of 2.90-25.20 nm. Green synthesized ZnO NPs exhibited moderate antibacterial activity against Gram-positive and Gram-negative bacteria and excellent DPPH free radical scavenging activity. Synthesized ZnO NPs had no toxic effects on the RAW 264.7 cell line. (C) 2014 Published by Elsevier Ltd.
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