Journal
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
Volume 24, Issue 9, Pages 2198-2201Publisher
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.bmcl.2014.03.008
Keywords
Chalcogenophosphate; Green synthesis; Antimicrobial activity; Statistical analysis; Seed germination assay
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Funding
- CSIR, New Delhi [02(0168)/13/EMR-II]
- DST, India
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We report in this work an environmentally benign zinc mediated synthesis of aryl and benzyl phosphorochalcogenoates in ethanol within a short reaction time. In vitro antimicrobial study along with statistical analysis and seed germination assay were performed. These chalcogenophosphates possess strong antimicrobial activity against the reference strains. The antibacterial activity was determined against four standard strains (Bacilus subtilis, Staphylococcus aureus, Escherichia coli, Pseudomonas aeruginosa). The antifungal activity was evaluated against one fungal strain Candida albicans. (C) 2014 Elsevier Ltd. All rights reserved.
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