Journal
TRANSLATIONAL NEUROSCIENCE
Volume 11, Issue 1, Pages 34-37Publisher
DE GRUYTER POLAND SP Z O O
DOI: 10.1515/tnsci-2020-0006
Keywords
Amputation stump; myoclonus; movement disorders; Botulinum toxin
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Funding
- National Research Foundation of Korea - Korean government [NRF-2019M3E5D1A02068106]
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Movement disorders post-amputation are a rare complication and can manifest as the jumping stump phenomenon, a form of peripheral myoclonus. The pathophysiology remains unknown and there is currently no standardized treatment. We describe the case of a 57-year-old male with unremitting stump myoclonus, starting one month after transtibial amputation, in his residual limb without associated phantom or neurological pain. The consequence of the myoclonus was a reduction in prosthetic wearing time. Failure to respond to oral medication led us to attempt the use of botulinum neurotoxin Type A injections in the involved muscles of the residual limb. Injection trials, over a two-year period, resulted in an improvement of movement disorder, an increased prosthetic wearing time and a higher satisfaction level of the patient. Injection of botulinum toxin type A should be considered as an alternative treatment for stump myoclonus to improve prosthetic wearing time and comfort.
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