☆ 4.5 Article

Regioselective synthesis of isoxazole-mercaptobenzimidazole hybrids and their in vivo analgesic and anti-inflammatory activity studies

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2013)

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Journal

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
Volume 23, Issue 5, Pages 1306-1309

Publisher

PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.bmcl.2012.12.101

Keywords

Isoxazole-benzimidazole hybrids; 1,3-Dipolar cycloaddition; N-Heterocyclic carbene; Analgesic activity; Anti-inflammatory activity

Categories

Chemistry, Medicinal Chemistry, Organic

Funding

  1. CSIR, New Delhi

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Regioselective synthesis of isoxazole-mercaptobenzimidazole hybrids and their efficiency in in vivo analgesic and anti-inflammatory activity was described. A comparison of structure-activity relationship for there compounds was also emphasized. (c) 2013 Elsevier Ltd. All rights reserved.

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