Journal
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
Volume 22, Issue 13, Pages 4246-4248Publisher
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.bmcl.2012.05.021
Keywords
Makomotake; Ustilago esculenta; Structure determination; Glioma cell; Synthesis
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Funding
- Grants-in-Aid for Scientific Research [24102513] Funding Source: KAKEN
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Makomotindoline (1) was isolated from Makomotake, Zizania latifolia infected with Ustilago esculenta. The structure was determined by the interpretation of spectroscopic data and synthesis. Makomotindoline (1), its L-Glc isomer (2) and its aglycon (3) were synthesized and their effects on rat glioma cells showed adverse effects on the cell growth. (C) 2012 Elsevier Ltd. All rights reserved.
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