4.5 Article

New bioactive macrocyclic diterpenoids from Jatropha multifida

Journal

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
Volume 21, Issue 22, Pages 6808-6810

Publisher

PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.bmcl.2011.09.032

Keywords

Multifidanol; Multifidenol; Jatropha multifida; Diterpenoid; Cytotoxicity; Antimicrobial activity

Funding

  1. UGC, New Delhi
  2. CSIR

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Two new macrocyclic diterpenoids, multifidanol (1) and multifidenol (2) along with several known compounds have been isolated from the stem of Jatropha multifida. The structures of the new compounds were established from the extensive studies of their 1D and 2D NMR spectra. The cytotoxic and antimicrobial activities of these two constituents were examined. (C) 2011 Elsevier Ltd. All rights reserved.

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