Journal
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
Volume 21, Issue 4, Pages 1257-1260Publisher
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.bmcl.2010.12.057
Keywords
Biofilms; Anti-biofilm; Antibiotic; 2-Aminoimidazole; Menthyl carbamate
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Funding
- University of North Carolina
- V Foundation for a Predoctoral Jimmy V Scholar
- NCSU Office of Undergraduate Research
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The successful marriage of structural features from our 2-aminoimidazole and menthyl carbamate classes of anti-biofilm agents has resulted in the development of a novel hybrid scaffold of biofilm modulators. The compounds were evaluated against a panel of four bacterial strains for anti-biofilm and anti-microbial activity. (C) 2010 Elsevier Ltd. All rights reserved.
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