Journal
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
Volume 20, Issue 14, Pages 4252-4258Publisher
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.bmcl.2010.05.025
Keywords
Spiroxindoles; 3-Cyanoacetyl indole; Anti-microbial activity; Pyran ring; Isatin
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Funding
- Council of Scientific and Industrial Research, New Delhi, India
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A simple and efficient method for the one-pot three-component synthesis of new spirooxindoles in room temperature is described. The newly synthesized spirooxindoles were screened for anti-microbial activity and the results are good on comparison with of standard antibacterial compounds. (C) 2010 Elsevier Ltd. All rights reserved.
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