Journal
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
Volume 20, Issue 20, Pages 6001-6007Publisher
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.bmcl.2010.08.073
Keywords
Synthesis; Benzothiadiazole; ESIPT; Live cell-imaging; Stem-cells
Categories
Funding
- CAPES
- CNPq
- FINEP
- Finatec
- FAPESP
- FAPDF
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Newly designed 2,1,3-benzothiadiazole-containing fluorescent probes with four excited state intramolecular proton transfer (ESIPT) sites were successfully tested in live cell-imaging assays using a confluent monolayer of human stem-cells (tissue). All tested dyes were compared with the commercially available DAPI and gave far better results. (c) 2010 Elsevier Ltd. All rights reserved.
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