4.7 Article

A route to virtually unlimited functionalization of water-soluble p-sulfonatocalix[4]arenes

Journal

CHEMICAL COMMUNICATIONS
Volume 56, Issue 29, Pages 4122-4125

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/d0cc01196g

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Funding

  1. Russian Foundation for Basic Research [18-33-00606]

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The functionality of p-sulfonatocalix[4]arenes can be easily extended using the propargylation/CuAAC reaction sequence, which allows the introduction of up to four substituted triazole units to the narrow rims of the macrocycles while maintaining their cone shapes and water solubility and, thus, biomedical applicability.

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