Journal
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
Volume 20, Issue 14, Pages 4193-4195Publisher
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.bmcl.2010.05.048
Keywords
Phenyl-azo-phenol; Synthesis; Antifungal activity; Phytopathogenic fungi
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Funding
- Program for New Century Excellent University Talents, State Education Ministry of China [NCET-06-0868]
- Key Project of Chinese Ministry of Education [107105]
- Higher Education of China [20070712025]
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As compared with a commercially available agricultural fungicide hymexazol, some phenyl-azo phenol derivatives (e.g., 4a, 4b, 4f, 4n, 4q, 4u, and 4v) exhibited the more promising and pronounced antifungal activities in vitro against seven phytopathogenic fungi. It seemed that 4-((un) substituted phenylazo)phenol and 4-((un) substituted phenylazo)-3-methylphenol might be considered as new lead structures for further design of agricultural fungicides. (C) 2010 Elsevier Ltd. All rights reserved.
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