Journal
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
Volume 20, Issue 15, Pages 4569-4572Publisher
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.bmcl.2010.06.015
Keywords
Verongid sponge; Pseudoceratina sp.; Bromotyrosine alkaloids; Ceratinadins A-C
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Funding
- Ministry of Education, Culture, Sports, Science, and Technology of Japan
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Three new bromotyrosine alkaloids, ceratinadins A-C (1-3), were isolated from an Okinawan marine sponge Pseudoceratina sp. and the structures of 1-3 were elucidated on the basis of spectroscopic data. Ceratinadin A (1) was a novel bromotyrosine alkaloid possessing an N-imidazolyl-quinolinone moiety. Ceratinadins A (1) and B (2) showed antifungal activity. (C) 2010 Elsevier Ltd. All rights reserved.
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