Journal
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
Volume 20, Issue 14, Pages 4108-4111Publisher
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.bmcl.2010.05.073
Keywords
Antibacterial; Gram-positive bacteria; Marine natural product; Dibromo olefin
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Funding
- NIH Intramural Research Program (NIDDK)
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Synthesis of the marine natural products motualevic acids A, E, and analogs in which modi. cations have been made to the omega-brominated lipid (E)-14,14-dibromotetra-deca-2,13-dienoic acid or amino acid unit are reported, together with antimicrobial activities against Staphylococcus aureus, methicillin-resistant S. aureus, Enterococcus faecium, and vancomycin-resistant Enterococcus. Published by Elsevier Ltd.
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