Journal
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
Volume 19, Issue 14, Pages 3963-3966Publisher
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.bmcl.2009.03.003
Keywords
Phosphonates; Synthesis; Immunology; PBMC; Activation of monocytes
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The synthesis and characterization of new series of phosphorus-containing dendrimers ended by nonsymmetrical azamonophosphonates, or azadiphosphonates, or azadiphosphonic acid salts are reported. The sodium salts of the non-symmetrical azadiphosphonic dendrimers are soluble in water. Their influence towards human immune blood cells is assayed ex vivo. (C) 2009 Elsevier Ltd. All rights reserved.
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