Journal
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
Volume 19, Issue 14, Pages 3875-3879Publisher
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.bmcl.2009.03.155
Keywords
Idraparinux; Heparin; Anticoagulant; Pentasaccharide; Synthesis
Categories
Funding
- National Natural Science Foundation of China [20572122, 20621062]
- Committee of Science and Technology of Shanghai [06XD14026, 04DZ19213]
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An efficient [DEF+GH] route was developed to the synthesis of Idraparinux, which is a fully O-sulfated, O-methylated mimic of the unique Antithrombin III binding domain of heparin. (C) 2009 Elsevier Ltd. All rights reserved.
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