Journal
SLEEP
Volume 44, Issue 11, Pages -Publisher
OXFORD UNIV PRESS INC
DOI: 10.1093/sleep/zsab166
Keywords
insomnia; sleep; cancer; stepped care; cognitive-behavioral therapy; web-based intervention
Categories
Funding
- Canadian Institutes of Health Research [125968]
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The study aimed to compare the efficacy of stepped care CBT-I and standard face-to-face CBT-I for insomnia symptoms in cancer patients. Results showed that stepped care CBT-I was not inferior to standard face-to-face intervention, making it a valuable approach for improving treatment accessibility for cancer patients.
Study Objectives: Cognitive-behavioral therapy for insomnia (CBT-I) is the recommended first-line treatment for cancer-related insomnia, but its accessibility is very limited in routine care. A stepped care approach has been recommended as a cost-effective way to make CBT-I more widely accessible. However, no controlled study has yet been published about the efficacy of this approach. The goal of this noninferiority randomized controlled trial (RCT) was to compare the short and long-term efficacy of a stepped care CBT-I (StepCBT-I) to a standard face-to-face CBT-I (StanCBT-I). Methods: A total of 177 cancer patients were randomized to: (1) StanCBT-I (6 face-to-face CBT-I sessions; n = 59) or (2) StepCBT-I (n = 118). In the StepCBT-I group, patients with less severe insomnia first received a web-based CBT-I (n = 65), while those with more severe insomnia received 6 face-to-face CBT-I sessions (n = 53). In both cases, patients could receive up to three booster sessions of CBT-I if they still had insomnia symptoms following this first step. Results: Results indicated that the Step-CBT-I group showed an Insomnia Severity Index score reduction and a sleep efficiency (on a sleep diary) increase that was not significantly inferior to that of StanCBT-I at all post-treatment time points. Analyses of secondary outcomes indicated significant time effects (ps <.001) and no significant group-by-time interactions (ps from.07 to.91) on other sleep diary parameters, sleep medication use, depression, anxiety, fatigue, and quality of life scores. Conclusion( s): The efficacy of stepped care CBT-I is not inferior to that of a standard face-to-face intervention and is a valuable approach to making this treatment more widely accessible to cancer patients.
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