Journal
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
Volume 19, Issue 9, Pages 2504-2508Publisher
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.bmcl.2009.03.034
Keywords
IKK2; IKK1; Azaindole; Kinase; IKK2 inhibitor
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The synthesis and SAR of a novel series of IKK2 inhibitors are described. Modi. cation around the hinge binding region of the 7-azaindole led to a series of potent and selective inhibitors with good cellular activity. (C) 2009 Elsevier Ltd. All rights reserved.
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