Journal
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
Volume 18, Issue 12, Pages 3541-3544Publisher
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.bmcl.2008.05.015
Keywords
oxazolidinone; RNA ligand; riboswitch; transcription; antitermination; T box
Categories
Funding
- NIGMS NIH HHS [GM61048, R01 GM061048-03, R01 GM061048-04, R01 GM047823, R01 GM047823-09, R01 GM047823-10, R01 GM073188-01A2, R01 GM061048-02, R01 GM073188-02, R01 GM073188, R01 GM061048-05, R01 GM047823-12, R01 GM061048, R01 GM061048-01A1, GM47823, GM073188, R01 GM047823-11] Funding Source: Medline
Ask authors/readers for more resources
The T box transcription antitermination system is a riboswitch found primarily in Gram-positive bacteria which monitors the aminoacylation of the cognate tRNA and regulates a variety of amino acid-related genes. Novel 4,5-disubstituted oxazolidinones were identified as high affinity RNA molecular effectors that modulate the transcription antitermination function of the T box riboswitch. (C) 2008 Elsevier Ltd. All rights reserved.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available
Share Paper
