4.5 Article

Tricyclic HIV integrase inhibitors: Potent and orally bioavailable C5-aza analogs

Journal

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
Volume 18, Issue 4, Pages 1388-1391

Publisher

PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.bmcl.2008.01.018

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A series of C5-aza tricyclic HIV integrase inhibitors was prepared. A highly potent and orally bioavailable compound ( compound 9) was identified and selected for development. (c) 2008 Elsevier Ltd. All rights reserved.

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