Related references
Note: Only part of the references are listed.PDE5 inhibitors enhance the lethality of standard of care chemotherapy in pediatric CNS tumor cells
Jane L. Roberts et al.
CANCER BIOLOGY & THERAPY (2014)
The discovery and development of cyclooxygenase-2 inhibitors as potential anticancer therapies
Mohsen Vosooghi et al.
EXPERT OPINION ON DRUG DISCOVERY (2014)
Nitric oxide inhibits autophagy via suppression of JNK in meniscal cells
Chao Shen et al.
RHEUMATOLOGY (2014)
Phosphodiesterase 5 Inhibitors Enhance Chemotherapy Killing in Gastrointestinal/Genitourinary Cancer Cells
Laurence Booth et al.
MOLECULAR PHARMACOLOGY (2014)
Targeting Hepatoma Using Nitric Oxide Donor Strategies
Raul Gonzalez et al.
ANTIOXIDANTS & REDOX SIGNALING (2013)
Dolastatin, along with Celecoxib, stimulates apoptosis by a mechanism involving oxidative stress, membrane potential change and PI3-K/AKT pathway down regulation
Honit Piplani et al.
BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS (2013)
Histone deacetylase inhibitors restore toxic BH3 domain protein expression in anoikis-resistant mammary and brain cancer stem cells, thereby enhancing the response to anti-ERBB1/ERBB2 therapy
Nichola Cruickshanks et al.
CANCER BIOLOGY & THERAPY (2013)
Enhanced apoptotic effects by downregulating Mcl-1: Evidence for the improvement of photodynamic therapy with Celecoxib
Jiaxing Song et al.
EXPERIMENTAL CELL RESEARCH (2013)
An update on pharmacological treatment of erectile dysfunction with phosphodiesterase type 5 inhibitors
Roberto Bruzziches et al.
EXPERT OPINION ON PHARMACOTHERAPY (2013)
Inhibition of autophagy and glycolysis by nitric oxide during hypoxia-reoxygenation impairs cellular bioenergetics and promotes cell death in primary neurons
Gloria A. Benavides et al.
FREE RADICAL BIOLOGY AND MEDICINE (2013)
Sorafenib and HDAC inhibitors synergize with TRAIL to kill tumor cells
Hossein A. Hamed et al.
JOURNAL OF CELLULAR PHYSIOLOGY (2013)
Induction but not inhibition of COX-2 confers human lung cancer cell apoptosis by celecoxib
Robert Ramer et al.
JOURNAL OF LIPID RESEARCH (2013)
P2X7 receptor-induced death of motor neurons by a peroxynitrite/FAS-dependent pathway
Mandi Gandelman et al.
JOURNAL OF NEUROCHEMISTRY (2013)
C22:0-and C24:0-dihydroceramides Confer Mixed Cytotoxicity in T-Cell Acute Lymphoblastic Leukemia Cell Lines
Michael W. Holliday et al.
PLOS ONE (2013)
Celecoxib-Induced Cytotoxic Effect Is Potentiated by Inhibition of Autophagy in Human Urothelial Carcinoma Cells
Kuo-How Huang et al.
PLOS ONE (2013)
Reactive nitrogen species regulate autophagy through ATM-AMPK-TSC2-mediated suppression of mTORC1
Durga N. Tripathi et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)
Inhibition of Sphingolipid Metabolism Enhances Resveratrol Chemotherapy in Human Gastric Cancer Cells
Kyong-Oh Shin et al.
BIOMOLECULES & THERAPEUTICS (2012)
OSU-03012 suppresses GRP78/BiP expression that causes PERK-dependent increases in tumor cell killing
Laurence Booth et al.
CANCER BIOLOGY & THERAPY (2012)
Nitric oxide (•NO) generation but not ROS plays a major role in silibinin-induced autophagic and apoptotic death in human epidermoid carcinoma A431 cells
Yang Yu et al.
FREE RADICAL RESEARCH (2012)
Obatoclax and Lapatinib Interact to Induce Toxic Autophagy through NOXA
Yong Tang et al.
MOLECULAR PHARMACOLOGY (2012)
Chemoprevention in familial adenomatous polyposis
Brian Kim et al.
BEST PRACTICE & RESEARCH CLINICAL GASTROENTEROLOGY (2011)
Lung Cancer Chemoprevention with Celecoxib in Former Smokers
Jenny T. Mao et al.
CANCER PREVENTION RESEARCH (2011)
Celecoxib Promotes c-FLIP Degradation through Akt-Independent Inhibition of GSK3
Shuzhen Chen et al.
CANCER RESEARCH (2011)
Nitric Oxide and Cyclic GMP Signaling Pathway as a Focus for Drug Development
A. Y. Kots et al.
CURRENT MEDICINAL CHEMISTRY (2011)
Activation of ceramide synthase 6 by celecoxib leads to a selective induction of C16:0-ceramide
Susanne Schiffmann et al.
BIOCHEMICAL PHARMACOLOGY (2010)
Celecoxib prevents tumor growth in an animal model by a COX-2 independent mechanism
Amanda Leite Bastos-Pereira et al.
CANCER CHEMOTHERAPY AND PHARMACOLOGY (2010)
Vorinostat and Sorafenib Increase CD95 Activation in Gastrointestinal Tumor Cells through a Ca2+-De novo Ceramide-PP2A-Reactive Oxygen Species-Dependent Signaling Pathway
Margaret A. Park et al.
CANCER RESEARCH (2010)
ERK/Ribosomal S6 Kinase (RSK) Signaling Positively Regulates Death Receptor 5 Expression through Co-activation of CHOP and Elk1
You-Take Oh et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2010)
Cytotoxic effects of celecoxib on Raji lymphoma cells correlate with aggravated endoplasmic reticulum stress but not with inhibition of cyclooxygenase-2
Szu-Ting Chen et al.
LEUKEMIA RESEARCH (2010)
cGMP-Dependent Protein Kinases and cGMP Phosphodiesterases in Nitric Oxide and cGMP Action
Sharron H. Francis et al.
PHARMACOLOGICAL REVIEWS (2010)
Sildenafil increases chemotherapeutic efficacy of doxorubicin in prostate cancer and ameliorates cardiac dysfunction
Anindita Das et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)
Pretreatment of sildenafil attenuates ischemia-reperfusion renal injury in rats
Dae Eun Choi et al.
AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY (2009)
The anti-proliferative potency of celecoxib is not a class effect of coxibs
Susanne Schiffmann et al.
BIOCHEMICAL PHARMACOLOGY (2008)
Aggravated endoplasmic reticulum stress as a basis for enhanced glioblastoma cell killing by bortezomib in combination with celecoxib or its non-coxib analogue, 2,5-dimethyl-celecoxib
Adel Kardosh et al.
CANCER RESEARCH (2008)
Selective COX2 inhibition improves whole body and muscular insulin resistance in fructose-fed rats
P-S. Hsieh et al.
EUROPEAN JOURNAL OF CLINICAL INVESTIGATION (2008)
Protein Kinase G-dependent Cardioprotective Mechanism of Phosphodiesterase-5 Inhibition Involves Phosphorylation of ERK and GSK3β
Anindita Das et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2008)
COX-2 inhibition is neither necessary nor sufficient for celecoxib to suppress tumor cell proliferation and focus formation in vitro
Huan-Ching Chuang et al.
MOLECULAR CANCER (2008)
N-(4-hydroxyphenyl)retinamide increases dihydroceramide and synergizes with dimethylsphingosine to enhance cancer cell
Hongtao Wang et al.
MOLECULAR CANCER THERAPEUTICS (2008)
Celecoxib-induced growth inhibition in SW480 colon cancer cells is associated with activation of protein kinase G
Jae-Won Soh et al.
MOLECULAR CARCINOGENESIS (2008)
OSU-03012 stimulates PKR-Like endoplasmic reticulum-dependent increases in 70-kDa heat shock protein expression, attenuating its lethal actions in transformed cells
Margaret A. Park et al.
MOLECULAR PHARMACOLOGY (2008)
Calcium-activated endoplasmic reticulum stress as a major component of tumor cell death induced by 2,5-dimethyl-celecoxib, a non-coxib analogue of celecoxib
Peter Pyrko et al.
MOLECULAR CANCER THERAPEUTICS (2007)
CD95 tyrosine phosphorylation is required for CD95 oligomerization
Andrea Eberle et al.
APOPTOSIS (2007)
OSU-03012 promotes caspase-independent but PERK-, cathepsin B-, BID-, and AIF-dependent killing of transformed cells
Adly Yacoub et al.
MOLECULAR PHARMACOLOGY (2006)
Cyclooxygenase-2 inhibition induces apoptosis signaling via death receptors and mitochondria in hepatocellular carcinoma
Michael A. Kern et al.
CANCER RESEARCH (2006)
Fifteen-year results of a randomized phase III trial of fenretinide to prevent second breast cancer
U. Veronesi et al.
ANNALS OF ONCOLOGY (2006)
Patient tumor EGFR and PDGFRA gene amplifications retained in an invasive intracranial xenograft model of glioblastoma multiforme
C Giannini et al.
NEURO-ONCOLOGY (2005)
CD95-tyrosine nitration inhibits hyperosmotic and CD95 ligand-induced CD95 activation in rat hepatocytes
R Reinehr et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Endoplasmic reticulum stress response is involved in nonsteroidal anti-inflammatory drug-induced apoptosis
S Tsutsumi et al.
CELL DEATH AND DIFFERENTIATION (2004)
Death receptor regulation and celecoxib-induced apoptosis in human lung cancer cells
XG Liu et al.
JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE (2004)
NO induced apoptosis of vascular smooth muscle cells accompanied by ceramide increase
CM Pilane et al.
JOURNAL OF CELLULAR PHYSIOLOGY (2004)
The development of COX2 inhibitors
RJ Flower
NATURE REVIEWS DRUG DISCOVERY (2003)
Basic fibroblast growth factor activates endothelial nitric-oxide synthase in CHO-K1 cells via the activation of ceramide synthesis
T Florio et al.
MOLECULAR PHARMACOLOGY (2003)
Fumonisin blunts nitric oxide-induced and nitroprusside-induced cardiornyocyte death
SW Rabkin
NITRIC OXIDE-BIOLOGY AND CHEMISTRY (2002)
COX-3, a cyclooxygenase-1 variant inhibited by acetaminophen and other analgesic/antipyretic drugs: Cloning, structure, and expression
NV Chandrasekharan et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2002)
Distinct roles for cyclooxygenases 1 and 2 in interleukin-1-induced behavioral changes
AH Swiergiel et al.
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2002)
Sildenafil for primary and secondary pulmonary hypertension
H Watanabe et al.
CLINICAL PHARMACOLOGY & THERAPEUTICS (2002)
Pharmacokinetics of sildenafil citrate after single oral doses in healthy male subjects: absolute bioavailability, food effects and dose proportionality
DJ Nichols et al.
BRITISH JOURNAL OF CLINICAL PHARMACOLOGY (2002)
Nitric oxide and cyclic guanosine monophosphate stimulate apoptosis via activation of the Fas-FasL pathway
MA Hayden et al.
JOURNAL OF SURGICAL RESEARCH (2001)
Ceramide enables Fas to cap and kill
A Cremesti et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
The cyclooxygenase-2 inhibitor celecoxib induces apoptosis by blocking Akt activation in human prostate cancer cells independently of Bcl-2
AL Hsu et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2000)