Journal
JOURNAL OF CELLULAR PHYSIOLOGY
Volume 230, Issue 5, Pages 959-968Publisher
WILEY
DOI: 10.1002/jcp.24807
Keywords
-
Categories
Funding
- CAPES
- CNPq
- FAPDF
- Fundect
Ask authors/readers for more resources
Several epidemiologic studies suggest that obesity and hypertension are associated with cardiac transcriptome modifications that could be further associated with inflammatory processes and cardiac hypertrophy. In this field, transcriptome studies have demonstrated their importance to elucidate physiologic mechanisms, pathways or genes involved in many biologic processes. Over the past decade, RNA microarray and RNA-seq analysis has become an essential component to examine metabolic pathways in terms of mRNA expression in cardiology. In this review, cardiac muscle gene expression in response to effects of obesity and hypertension will be focused, providing a broad view on cardiac transcriptome and physiologic and biochemical mechanisms involved in gene expression changes produced by these events, emphasizing the use of new technologies for gene expression analyses. J. Cell. Physiol. 230: 959-968, 2015. (c) 2014 Wiley Periodicals, Inc., A Wiley Company
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available