Journal
BMJ CASE REPORTS
Volume 14, Issue 1, Pages -Publisher
BMJ PUBLISHING GROUP
DOI: 10.1136/bcr-2020-237690
Keywords
adrenal disorders; fluid electrolyte and acid-base disturbances
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SARS-CoV-2, the virus causing COVID-19, can lead to adrenal insufficiency in patients. Early diagnosis and treatment are crucial for improving patient outcomes.
SARS-CoV-2 is the cause of COVID-19. Since the outbreak and rapid spread of COVID-19, it has been apparent that the disease is having multi-organ system involvement. Still its effect in the endocrine system is not fully clear and data on cortisol dynamics in patients with COVID-19 are not yet available. SARS-CoV-2 can knock down the host's cortisol stress response. Here we present a case of a 51-year-old man vomiting for 10 days after having confirmed COVID-19 infection. He had hypotension and significant hyponatraemia. Work-up was done including adrenocorticotropic hormone stimulation test. He was diagnosed as suffering from adrenal insufficiency and started on steroids with subsequent improvement in both blood pressure and sodium level. COVID-19 can cause adrenal insufficiency. Clinicians must be vigilant about the possibility of an underlying relative cortisol deficiency in patients with COVID-19.
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