Journal
BIOORGANIC & MEDICINAL CHEMISTRY
Volume 17, Issue 14, Pages 5275-5284Publisher
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.bmc.2009.05.039
Keywords
Antioxidant; Radioprotection; Phosphorothioates; Thiosulfonic acid; Benzothiazole; Thiadiazole
Funding
- 'Delegation Generale pour l'Armement' [DGA/DSP/STTC/DT/DH]
- Ministere de la Defense Nationale, France
Ask authors/readers for more resources
In this work, we report the synthesis and characterization of new compounds derived from benzothiazoles and thiadiazoles. We observed that structural modi. cations on these skeletons affected the antioxidant activity. Thiol and aminothiol compounds derived from thiadiazoles and benzothiazoles showed an interesting antioxidant property. The radioprotective activity has also been evaluated in mice. Some of these compounds could be good radioprotectors. (C) 2009 Elsevier Ltd. All rights reserved.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available