Journal
BIOORGANIC & MEDICINAL CHEMISTRY
Volume 17, Issue 6, Pages 2121-2136Publisher
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.bmc.2008.11.025
Keywords
Myxobacteria; Secondary metabolism; Myxovirescin; Genome mining
Funding
- Deutsche Forschungsgemeinschaft (DFG)
- Bundesministerium fur Bildung und Forschung (BMB + F)
- Alexander von Humboldt Foundation
Ask authors/readers for more resources
Myxobacteria are soil-dwelling, Gram-negative bacteria which are notable not only for their multi-cellular 'social' lifestyles, but for production of structurally diverse secondary metabolites with potential in clinical therapy. Here we briefly review the history of myxobacterial natural products research, provide an overview of their unique secondary metabolism, with an emphasis on assembly line biosynthesis of polyketide and non-ribosomal peptide metabolites, and look to the future of the field. (C) 2008 Elsevier Ltd. All rights reserved.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available