Journal
EUROPEAN JOURNAL OF CARDIO-THORACIC SURGERY
Volume 62, Issue 1, Pages -Publisher
OXFORD UNIV PRESS INC
DOI: 10.1093/ejcts/ezac325
Keywords
Distal stent graft-induced new entry; Frozen elephant trunk; Aortic dissection; Multicenter study
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This study investigated the incidence and predictive factors of distal stent graft-induced new entry (d-SINE) after the frozen elephant trunk technique for aortic dissection, finding that onset time >48 h was an independent predictor. The results suggest that preemptive endovascular repair may be appropriate for protecting new entry in high-risk patients.
OBJECTIVES: The incidence rate of distal stent graft-induced new entry (d-SINE) after frozen elephant trunk technique for aortic dissection remains controversial. The aim of this study was to investigate the incidence and seek the clinical and anatomical predictive factors. METHODS: This study is a retrospective multicentre evaluation of complications including d-SINE, aortic events and reintervention after the frozen elephant trunk procedure for aortic dissection. RESULTS: Our cohort included a total of 177 consecutive patients who underwent the frozen elephant trunk procedure for acute and chronic aortic dissection at 5 centres in Japan from May 2014 to March 2021. The incidence rate of d-SINE was 14.1% (25/177 patients). The cumulative incidence of d-SINE was 7.1%, 12.4% and 21.4% after 12, 36 and 60 months, respectively. d-SINE was not associated with mid-term survival rate. After competing risk regression analysis, onset time >48 h (subdistribution hazard ratio, 3.80; 95% confidence interval, 1.13-12.79; P = 0.031) was detected as an independent predictor. CONCLUSIONS: Awareness that there is a relatively higher incidence of d-SINE after frozen elephant trunk procedures is important. Nonhyper-acute phase was detected as an independent risk factor. Pre-emptive endovascular repair may be appropriate to protect new entry in high-risk patients.
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