Journal
IEEE-ASME TRANSACTIONS ON MECHATRONICS
Volume 27, Issue 5, Pages 2829-2840Publisher
IEEE-INST ELECTRICAL ELECTRONICS ENGINEERS INC
DOI: 10.1109/TMECH.2021.3121267
Keywords
Electromagnetic systems; magnetic control; medical robots; microrobots; ultrasound imaging
Categories
Funding
- Multi-scale Medical Robotics Center (MRC)
- SIAT-CUHK Joint Laboratory of Robotics and Intelligent Systems
- InnoHK at the Hong Kong Science Park
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This article proposes a robotic solution to improve the endovascular intervention for occlusive peripheral vascular disease, addressing concerns such as low success rate, undesired trauma, and radiation exposure. The miniature magnetic driller-tipped guidewire (MDG) and integrated actuation system successfully achieve controllability and penetrability in navigating through complex vasculature and clogged regions, while reducing radiation hazards through US imaging guidance.
The endovascular intervention has been widely used to treat occlusive peripheral vascular disease (PVD). However, the current procedure has concerns such as low successful rate, undesired trauma, and radiation exposure. This article proposes a robotic solution to mitigate these limitations. A miniature magnetic driller-tipped guidewire (MDG) is designed, which performs 1) controllable bending under directional magnetic fields to navigate in complex vasculature and 2) mechanical drilling under rotating magnetic fields to pass through clogged regions. An integrated actuation system is adopted for magnetic control and ultrasound (US) imaging in a large workspace. A control framework composed of the preoperative and intraoperative stages is developed, which internally coordinates all system modules, addresses noisy US imaging, and provides convenient operation. Demonstrations under an optical camera verify the flexible steering ability and effective unclogging motion of the MDG. Furthermore, US image-monitored in vitro experiments validate the overall hardware platform and control strategy. The designed MDG realizes dual objectives, including controllability at bifurcations and penetrability at clots. The introduced US imaging modality largely reduces radiation hazards in conventional catheterization. This article studies the intervention of the MDG under electromagnetic field navigation and US imaging guidance. The proposed workflow has the potential to improve operational safety and clinical outcomes of the occlusive PVD treatment.
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