4.7 Article

Synthesis and biological evaluation of asymmetric gramicidin S analogues containing modified D-phenylalanine residues

Journal

BIOORGANIC & MEDICINAL CHEMISTRY
Volume 17, Issue 17, Pages 6318-6328

Publisher

PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.bmc.2009.07.042

Keywords

Anti-microbial peptides; Gramicidin S derivatives; Biological profile

Funding

  1. STW [07109]
  2. Spanish Ministry of Science and Innovation [BFU2008-01588/BMC]

Ask authors/readers for more resources

The synthesis of new analogues of the cationic antimicrobial peptide gramicidin S, having a modified D-phenylalanine residue, their antibacterial properties against several Gram positive and negative strains, as well as their hemolytic activity is reported. (C) 2009 Elsevier Ltd. All rights reserved.

Authors

I am an author on this paper
Click your name to claim this paper and add it to your profile.

Reviews

Primary Rating

4.7
Not enough ratings

Secondary Ratings

Novelty
-
Significance
-
Scientific rigor
-
Rate this paper

Recommended

No Data Available
No Data Available